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Moreover, a element of endothelial dysfunction has been proposed, which can contribute to irregular vessel reactivity. However, testosterone in physiologic doses may even be beneficial in patients with angina , have greater ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in males with established coronary artery disease . Therefore, an interaction of endogenous factors of the patient’s risk profile in addition to the testosterone dosing could additionally be problems with whether or not antagonistic events happen.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac risk elements utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient also had polycythemia, doubtless secondary to high-dose testosterone. The affected person underwent profitable percutaneous intervention of the best coronary artery. Physicians and sufferers ought to pay attention to the scientific consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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